ABSTRACT
COVID-19 has been associated with a hypercoagulable state and thrombotic events. Venous thromboembolism has been the most commonly reported type of thrombosis but also arterial thrombosis and disseminated intravascular coagulation in inpatients have been described frequently in several clinical experiences. Patients with COVID-19, because of its tendency to induce leucopenia and overlapping of bacterial infection, may experience sudden disseminated intravascular coagulation (DIC), as in the case that we report here. However, early diagnosis and treatment may be associated with positive resolution of these severe complications.
Subject(s)
COVID-19/complications , Disseminated Intravascular Coagulation/virology , Neutropenia/virology , SARS-CoV-2 , Sepsis/virology , COVID-19/virology , Humans , Male , Middle AgedSubject(s)
COVID-19/pathology , Filgrastim/therapeutic use , Hematologic Agents/therapeutic use , Neutropenia/drug therapy , Neutropenia/virology , Antibodies, Viral/blood , Humans , Immunoglobulin G/blood , Immunoglobulin M/blood , Infant , Leukocyte Count , Male , Neutropenia/pathology , Neutrophils/cytology , SARS-CoV-2Subject(s)
Betacoronavirus , Coronavirus Infections/epidemiology , Hospitalization , Pneumonia, Viral/epidemiology , Breast Feeding , COVID-19 , Cough/virology , Female , Fever/virology , Gastroesophageal Reflux , Glucocorticoids/therapeutic use , Heart Defects, Congenital , Humans , Infant , Infant, Newborn , Infant, Premature , Length of Stay/statistics & numerical data , Lung/diagnostic imaging , Lymphocytosis/virology , Male , Neutropenia/virology , New York/epidemiology , Pandemics , Pediatric Obesity , Procalcitonin/blood , Radiography , Respiratory Distress Syndrome, Newborn , SARS-CoV-2 , Tobacco Smoke PollutionABSTRACT
Between March 10, 2020 and April 17, 2020, of 8/70 (11.4%) SARS-CoV-2 positive infants that presented, 5/8 (63%) developed fever, 4/8 (50%) had lower respiratory tract involvement, 2/8 (25%) had neutropenia and thrombocytosis, and 4/8 infants (50%) were treated for suspected sepsis with broad-spectrum antibiotics. Only 1/8 (13%) required pediatric intensive care. All patients were eventually discharged home well.